Polymetal International was the biggest faller in early trading on the FTSE 100 index, as investors remained concerned over further weakness in the price of the yellow metal.
The gold producer saw its share price drop by 2.5% early on (at 0807 GMT), falling to 990.5p.
It was joined at the bottom by insurer Aviva, down 1.8% to 360.7p, and engineer Weir Group, dropping 1.6% to 1,908p.
Copper miner Kazakhmys fell 1.5% to 937.5p, while peer Rio Tinto dropped 1.4% to 3,374p.
The biggest riser was drug maker AstraZeneca, climbing 0.6% higher to 2,858p (at 0806 GMT). Pharmaceuticals company GlaxoSmithKline also increased early on rising 0.4% to 1,409.5p.
National Grid rose by 0.3% to 651p, as did real estate investment trust Land Securities, up to 693.5p.
Another property investor, shopping mall operator Capital Shopping Centres saw its share price rise by 0.2% to 336.9p.